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1

Large scale purification and refolding of HIV-1 protease fromEscherichia coliinclusion bodies

John O. Hui, Alfredo G. Tomasselli, Ilene M. Reardon, June M. Lull, David P. Brunner, Che-Shen C. Tomich, Robert L. Heinrikson

Journal:

The Protein Journal

Year:

1993

Language:

english

File:

PDF, 450 KB

english, 1993

2

Amino acid analysis by reverse-phase high-performance liquid chromatography: Precolumn derivatization with phenylisothiocyanate

Robert L. Heinrikson, Stephen C. Meredith

Journal:

Analytical Biochemistry

Year:

1984

Language:

english

File:

PDF, 789 KB

english, 1984

3

The covalent and tertiary structure of bovine liver rhodanese

Ploegman, Jan H., Drent, Gé, Kalk, Kor H., Hol, Wim G. J., Heinrikson, Robert L., Keim, Philip, Weng, Litai, Russell, John

Journal:

Year:

1978

File:

PDF, 603 KB

1978

4

Triphosphopyridine nucleotide specific isocitrate dehydrogenase from Azotobacter vinelandii. Alkylation of a specific methionine residue and amino acid sequence of the peptide containing this residue

Edwards, David J., Heinrikson, Robert L., Chung, Albert E.

Journal:

Year:

1974

Language:

english

File:

PDF, 879 KB

english, 1974

5

[Methods in Enzymology] Enzyme Structure Part E Volume 47 || [20] Applications of thermolysin in protein structural analysis

Heinrikson, Robert L.

Year:

1977

Language:

english

File:

PDF, 858 KB

english, 1977

6

Predicting human immunodeficiency virus protease cleavage sites in proteins by a discriminant function method

Chou, Kuo-Chen, Tomasselli, Alfredo G., Reardon, Ilene M., Heinrikson, Robert L.

Journal:

Proteins: Structure, Function, and Bioinformatics

Year:

1996

Language:

english

File:

PDF, 1.53 MB

english, 1996

7

Human β-Secretase (BACE) and BACE Inhibitors.

Varghese John, James P. Beck, Michael J. Bienkowski, Sukanto Sinha, Robert L. Heinrikson

Journal:

Year:

2004

File:

PDF, 52 KB

2004

8

Could angiotensin I be produced from a renin substrate by the HIV-1 protease?

Satish K. Sharma, David B. Evans, John O. Hui, Robert L. Heinrikson

Journal:

Analytical Biochemistry

Year:

1991

Language:

english

File:

PDF, 446 KB

english, 1991

9

Kinetic and structural characterization of caspase-3 and caspase-8 inhibition by a novel class of irreversible inhibitors

Zhigang Wang, William Watt, Nathan A. Brooks, Melissa S. Harris, Jan Urban, Douglas Boatman, Michael McMillan, Michael Kahn, Robert L. Heinrikson, Barry C. Finzel, Arthur J. Wittwer, James Blinn, Satw

Journal:

Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics

Year:

2010

Language:

english

File:

PDF, 2.04 MB

english, 2010

10

Employing a superior BACE1 cleavage sequence to probe cellular APP processing

Alfredo G. Tomasselli, Isam Qahwash, Thomas L. Emmons, Yifeng Lu, Joseph W. Leone, June M. Lull, Kam F. Fok, Carol A. Bannow, Clark W. Smith, Michael J. Bienkowski, Robert L. Heinrikson, Riqiang Yan

Journal:

Journal of Neurochemistry

Year:

2003

Language:

english

File:

PDF, 370 KB

english, 2003

11

Crystal structure of a complex of HIV-1 protease with a dihydroxyethylene-containing inhibitor: Comparisons with molecular modeling

Narmada Thanki, J.K. Mohana Rao, Stephen I. Foundling, Alexander Wlodawer, W. Jeffrey Howe, Joseph B. Moon, John O. Hui, Alfredo G. Tomasselli, Robert L. Heinrikson, Suvit Thaisrivongs

Journal:

Protein Science

Year:

1992

Language:

english

File:

PDF, 1.11 MB

english, 1992

12

Human immunodeficiency virus type-1 reverse transcriptase and ribonuclease h as substrates of the viral protease

Alfredo G. Tomasselli, Jean L. Sarcich, Linda J. Barrett, Ilene M. Reardon, W. Jeffrey Howe, David B. Evans, Satish K. Sharma, Robert L. Heinrikson

Journal:

Protein Science

Year:

1993

Language:

english

File:

PDF, 3.15 MB

english, 1993

13

Isolation and characterization of native human renin derived from Chinese hamster ovary cells

Dr. Roger A. Poorman, Daniel P. Palermo, Leonard E. Post, Kazuo Murakami, John H. Kinner, Clark W. Smith, Ilene Reardon, Robert L. Heinrikson

Journal:

Proteins: Structure, Function, and Bioinformatics

Year:

1986

Language:

english

File:

PDF, 927 KB

english, 1986

14

Calcium-free calmodulin is a substrate of proteases from human immunodeficiency viruses 1 and 2

Alfredo G. Tomasselli, W. Jeffrey Howe, John O. Hui, Tomi K. Sawyer, Ilene M. Reardon, Dianne L. DeCamp, Charles S. Craik, Robert L. Heinrikson

Journal:

Proteins: Structure, Function, and Bioinformatics

Year:

1991

Language:

english

File:

PDF, 887 KB

english, 1991

15

An examination of structural interactions presumed to be of importance in the stabilization of phospholipase A2dimers based upon comparative protein sequence analysis of a monomeric and dimeric enzyme from the venom ofAgkistrodon p. piscivorus

William Welches, Ilene Reardon, Robert L. Heinrikson

Journal:

The Protein Journal

Year:

1993

Language:

english

File:

PDF, 705 KB

english, 1993

16

Evolution of phosphofructokinase—gene duplication and creation of new effector sites

Poorman, Roger A., Randolph, Anne, Kemp, Robert G., Heinrikson, Robert L.

Journal:

Year:

1984

File:

PDF, 354 KB

1984

17

Phospholipases A2: Variations on a structural theme and their implications as to mechanism

John M. Maraganore, Roger A. Poorman, Robert L. Heinrikson

Journal:

The Protein Journal

Year:

1987

Language:

english

File:

PDF, 933 KB

english, 1987

18

Primary structure of avian hepatic rhodanese

Ronald A. Kohanski, Robert L. Heinrikson

Journal:

The Protein Journal

Year:

1990

Language:

english

File:

PDF, 742 KB

english, 1990

19

Partial structural analysis of the basic chromosomal protein of rat spermatozoa

W. Stephen Kistler, Pamela S. Keim, Robert L. Heinrikson

Journal:

Biochimica et Biophysica Acta (BBA) - Protein Structure

Year:

1976

Language:

english

File:

PDF, 353 KB

english, 1976

20

Studies on human α-fetoprotein: Isolation and characterization of monomeric and polymeric forms and amino-terminal sequence analysis

Stanley Yachnin, Robert Hsu, Robert L. Heinrikson, J.Bruce Miller

Journal:

Biochimica et Biophysica Acta (BBA) - Protein Structure

Year:

1977

Language:

english

File:

PDF, 850 KB

english, 1977

21

Juvenile hormone carrier protein of Manduca sexta haemolymph. Improved purification procedure; protein modification studies and sequence of the amino terminus of the protein

Ronald C. Peterson, Peter E. Dunn, Hidelisa L. Seballos, Barbara K. Barbeau, Pamela S. Keim, Clark T. Riley, Robert L. Heinrikson, John H. Law

Journal:

Insect Biochemistry

Year:

1982

Language:

english

File:

PDF, 614 KB

english, 1982

22

Targeting the HIV-protease in AIDS therapy: a current clinical perspective

Alfredo G. Tomasselli, Robert L. Heinrikson

Journal:

Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology

Year:

2000

Language:

english

File:

PDF, 1.40 MB

english, 2000

23

Cation binding to the integrin CD11b I domain and activation model assessment

Eric T Baldwin, Ronald W Sarver, Garold L Bryant Jr, Kimberly A Curry, Michael B Fairbanks, Barry C Finzel, Robert L Garlick, Robert L Heinrikson, Nancy C Horton, Laura-Lee C Kelley, Ana M Mildner, Jo

Journal:

Year:

1998

Language:

english

File:

PDF, 809 KB

english, 1998

24

The atomic-resolution structure of human caspase-8, a key activator of apoptosis

William Watt, Kenneth A Koeplinger, Ana M Mildner, Robert L Heinrikson, Alfredo G Tomasselli, Keith D Watenpaugh

Journal:

Year:

1999

Language:

english

File:

PDF, 197 KB

english, 1999

25

Amino acid sequence of a 12-kDa inhibitor of protein kinase C

Ned M. MOZIER, Heidi A. ZÜRCHER-NEELY, David M. GUIDO, W. Rodney MATHEWS, Robert L. HEINRIKSON, Elaine D. FRASER, Michael P. WALSH, James D. PEARSON

Journal:

Year:

1990

Language:

english

File:

PDF, 452 KB

english, 1990

26

A Model of the Complex between Cyclin-Dependent Kinase 5 and the Activation Domain of Neuronal Cdk5 Activator

Kuo-Chen Chou, Keith D. Watenpaugh, Robert L. Heinrikson

Journal:

Biochemical and Biophysical Research Communications

Year:

1999

Language:

english

File:

PDF, 581 KB

english, 1999

27

Production of Chemokines CTAPIII and NAP/2 by Digestion of Recombinant Ubiquitin–CTAPIII with Yeast Ubiquitin C-Terminal Hydrolase and Human Immunodeficiency Virus Protease

Ana M. Mildner, Donna J. Paddock, Lloyd W. LeCureux, Joseph W. Leone, Donald C. Anderson, Alfredo G. Tomasselli, Robert L. Heinrikson

Journal:

Protein Expression and Purification

Year:

1999

Language:

english

File:

PDF, 155 KB

english, 1999

28

[W206R]-Procaspase 3: An Inactivatable Substrate for Caspase 8

Kenneth B. Rank, Ana M. Mildner, Joseph W. Leone, Kenneth A. Koeplinger, K.C. Chou, Alfredo G. Tomasselli, Robert L. Heinrikson, Satish K. Sharma

Journal:

Protein Expression and Purification

Year:

2001

Language:

english

File:

PDF, 799 KB

english, 2001

29

Covalent structural analysis of yeast inorganic pyrophosphatase: Location of groups implicated in the catalytic function; placement of the NH2-terminal 100 residues in the subunit

Richard Sterner, Robert L. Heinrikson

Journal:

Archives of Biochemistry and Biophysics

Year:

1975

Language:

english

File:

PDF, 1004 KB

english, 1975

30

Chloroplast and cytoplasmic enzymes: Subunit structure of pea leaf aldolases

Louise E. Anderson, Robert L. Heinrikson, Claudia Noyes

Journal:

Archives of Biochemistry and Biophysics

Year:

1975

Language:

english

File:

PDF, 878 KB

english, 1975

31

Crotalus adamanteus phospholipase A2-α: Subunit structure, NH2-terminal sequence, and homology with other phospholipases

Francis H.C. Tsao, Pamela S. Keim, Robert L. Heinrikson

Journal:

Archives of Biochemistry and Biophysics

Year:

1975

Language:

english

File:

PDF, 1.03 MB

english, 1975

32

Structural studies of Bacillus subtilis glutamine synthetase: Further purification, sulfhydryl groups, and the NH2-terminal amino acid sequence

Robert Hsu, Sherwin J. Singer, Pamela Keim, Thomas F. Deuel, Robert L. Heinrikson

Journal:

Archives of Biochemistry and Biophysics

Year:

1977

Language:

english

File:

PDF, 723 KB

english, 1977

33

The covalent structure of pig kidney fructose 1,6-bisphosphatase: sequence of the 60-residue NH2-terminal peptide produced by digestion with subtilisin

Frank Marcus, Ida Edelstein, Leo J. Saidel, Pamela S. Keim, Robert L. Heinrikson

Journal:

Archives of Biochemistry and Biophysics

Year:

1981

Language:

english

File:

PDF, 1.17 MB

english, 1981

34

Glutathione-related inhibition of prostaglandin metabolism

Rhoda Feldman, Amelita Luncsford, Robert L. Heinrikson, John Westley, Joseph Jarabak

Journal:

Archives of Biochemistry and Biophysics

Year:

1981

Language:

english

File:

PDF, 1.16 MB

english, 1981

35

Isolation and sequence determination of an active site peptide of rabbit muscle pyruvate kinase

Guillermo Bezares, Jaime Eyzaguirre, Maria Victoria Hinrichs, Robert L. Heinrikson, Ilene Reardon, Robert G. Kemp, Steven P. Latshaw, Sergio Bazaes

Journal:

Archives of Biochemistry and Biophysics

Year:

1987

Language:

english

File:

PDF, 478 KB

english, 1987

36

Chloroplast and cytoplasmic enzymes: Isolation and sequencing of cDNAs coding for two distinct pea chloroplast aldolases

Kuldeep Razdan, Robert L. Heinrikson, Heidi Zurcher-Neely, Paul W. Morris, Louise E. Anderson

Journal:

Archives of Biochemistry and Biophysics

Year:

1992

Language:

english

File:

PDF, 648 KB

english, 1992

37

Studies of the cyanogen bromide fragments of the apoprotein of human serum low density lipoproteins

Dale G. Deutsch, Robert L. Heinrikson, James Foreman, Angelo M. Scanu

Journal:

Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism

Year:

1978

Language:

english

File:

PDF, 1.09 MB

english, 1978

38

Relation between binding and the action of phospholipases A2 on Escherichia coli exposed to the bactericidal/permeability-increasing protein of neutrophils

Steven Forst, Jerrold Weiss, John M. Maraganore, Robert L. Heinrikson, Peter Elsbach

Journal:

Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism

Year:

1987

Language:

english

File:

PDF, 495 KB

english, 1987

39

Structural studies of bovine liver thiosulfate sulfurtransferase III. Isolation and sequence analysis of the tryptic peptides containing tryptophan

Robert L. Heinrikson, John Russell

Journal:

Biochimica et Biophysica Acta (BBA) - Protein Structure

Year:

1972

Language:

english

File:

PDF, 587 KB

english, 1972

40

Structural studies of bovine liver thiosulfate sulfurtransferase II. S-carboxymethylation of the enzyme and sequence analysis of the tryptic cysteinyl peptides

Kenneth M. Blumenthal, Robert L. Heinrikson

Journal:

Biochimica et Biophysica Acta (BBA) - Protein Structure

Year:

1972

Language:

english

File:

PDF, 1009 KB

english, 1972

41

The role of lysyl residues of phospholipases A2 in the formation of the catalytic complex

John M. Maraganore, Robert L. Heinrikson

Journal:

Biochemical and Biophysical Research Communications

Year:

1985

Language:

english

File:

PDF, 434 KB

english, 1985

42

Comparison of enzymatic and pharmacological activities of lysine-49 and aspartate-49 phospholipases A2 from Agkistrodon piscivorus piscivorus snake venom

Daljit S. Dhillon, Eleonora Condrea, John M. Maraganore, Robert L. Heinrikson, Sheila Benjamin, Philip Rosenberg

Journal:

Biochemical Pharmacology

Year:

1987

Language:

english

File:

PDF, 877 KB

english, 1987

43

Purification and structural characterization of the CD11b/CD18 integrin α subunit I domain reveals a folded conformation in solution

Michael B. Fairbanks, John R. Pollock, Mark D. Prairie, Terrence A. Scahill, Lubo Baczynskyj, Robert L. Heinrikson, Brian J. Stockman

Journal:

Year:

1995

Language:

english

File:

PDF, 600 KB

english, 1995

44

Activity of recombinant cysteine-rich domain proteins derived from the membrane-bound MUC17/Muc3 family mucins

Samuel B. Ho, Ying Luu, Laurie L. Shekels, Surinder K. Batra, Brandon Kandarian, David B. Evans, Phillip G. Zaworski, Cindy L. Wolfe, Robert L. Heinrikson

Journal:

Biochimica et Biophysica Acta (BBA) - General Subjects

Year:

2010

Language:

english

File:

PDF, 1.96 MB

english, 2010

45

Human intestinal MUC17 mucin augments intestinal cell restitution and enhances healing of experimental colitis

Ying Luu, Wade Junker, Satyanarayana Rachagani, Srustidhar Das, Surinder K. Batra, Robert L. Heinrikson, Laurie L. Shekels, Samuel B. Ho

Journal:

The International Journal of Biochemistry & Cell Biology

Year:

2010

Language:

english

File:

PDF, 1.18 MB

english, 2010

46

An efficient method to express and refold a truncated human procaspase-9: A caspase with activity toward Glu-X bonds

Ramkrishna Sadhukhan, Joseph W. Leone, June Lull, Zhigang Wang, Rolf F. Kletzien, Robert L. Heinrikson, Alfredo G. Tomasselli

Journal:

Protein Expression and Purification

Year:

2006

Language:

english

File:

PDF, 302 KB

english, 2006

47

Heterodimer formation is essential for heparanase enzymatic activity

Flonia Levy-Adam, Hua-Quan Miao, Robert L Heinrikson, Israel Vlodavsky, Neta Ilan

Journal:

Biochemical and Biophysical Research Communications

Year:

2003

Language:

english

File:

PDF, 255 KB

english, 2003

48

Prediction of the tertiary structure of a caspase-9/inhibitor complex

Kuo-Chen Chou, Alfredo G. Tomasselli, Robert L. Heinrikson

Journal:

Year:

2000

Language:

english

File:

PDF, 857 KB

english, 2000

49

Prediction of the tertiary structure and substrate binding site of caspase-8

Kuo-Chen Chou, David Jones, Robert L Heinrikson

Journal:

Year:

1997

Language:

english

File:

PDF, 863 KB

english, 1997

50

Caspase 8: An Efficient Method for Large-Scale Autoactivation of Recombinant Procaspase 8 by Matrix Adsorption and Characterization of the Active Enzyme

Kenneth A. Koeplinger, Ana M. Mildner, Joseph W. Leone, Jean S. Wheeler, Robert L. Heinrikson, Alfredo G. Tomasselli

Journal:

Protein Expression and Purification

Year:

2000

Language:

english

File:

PDF, 189 KB

english, 2000